IER3 抗体 (PE)
Quick Overview for IER3 抗体 (PE) (ABIN901746)
抗原
See all IER3 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human IEX1/Differentiation dependent gene 2 protein
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亚型
- IgG
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anti-Immediate Early Response 3 (IER3) (AA 45-73), (N-Term) antibody
IER3 适用: 人, 小鼠 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Immediate Early Response 3 (IER3) (C-Term) antibodyIER3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Immediate Early Response 3 (IER3) (AA 38-65), (N-Term) antibodyIER3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB20475 unconjugated
anti-Immediate Early Response 3 (IER3) (AA 85-156) antibodyIER3 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Immediate Early Response 3 (IER3) (AA 1-82) antibodyIER3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- IER3 (Immediate Early Response 3 (IER3))
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别名
- IEX1
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背景
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Synonyms: DIF2, IEX1, PRG1, DIF-2, GLY96, IEX-1, IEX-1L, Radiation-inducible immediate-early gene IEX-1, Differentiation-dependent gene 2 protein, Protein DIF-2, Immediate early protein GLY96, Immediate early response 3 protein, PACAP-responsive gene 1 protein, Protein PRG1, IER3
Background: May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.
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分子量
- 17kDa
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基因ID
- 8870
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UniProt
- P46695
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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